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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca82f8b67a4933bbeea2f9393dc8bab3b48f71442a23196b785b8f9d9fea7b36' 
  AND token = 'zUPQmxIz3z5qBQ8GsWjeWsgvsgVngREXVm0EsnzbGFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}