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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b8730e81c4269e4ca60f9ed17b7fa02a170e451da52529c7fc3d6573f3c84e' 
  AND token = 'yILmn4ho10qeiDsEUrrPn84gGLudpgOuB7guF+nx7DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}