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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f635f0bb516a280d20464ea20e180c2188392985f9f38443dc1bed551d4ccd' 
  AND token = 'Z/WC0RrCY/4QppY0X32x/Cx8gqi4ZbbqxxxhSnBeRwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}