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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49a887a809fac63ef2d9702b14f5cf6f46eb0441a7da1ecc2a309576eac8061' 
  AND token = 'sQXCme4+bMHQj6zzyCMGKI8f8tOT73uC7xnV4n9P5aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}