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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961041c8e3f29aca6c9ea21f1ace74b5996634e5e591556c2a08533471da903f' 
  AND token = 'nEZsaj/RdXBdCDal7Dg4Q2OuDG0fuswTDFxIefQlMVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}