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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01751d3b1618b9e62f8ad787405e8b78a4c14117c3c510c6e8b8dd21c909497c' 
  AND token = 'nehPwwRVqMd/zD4JSwJeUlC2EgJRdB/JgIUdju4jfD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}