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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4c068b9b798a0c8ad187d5cc236cb63a8ec366df536c7dd7465647e06c0f72' 
  AND token = 'xPw2LWpKhyZBM3oUBz0KC/HRT6cFTSRhoaHgv2eaCP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}