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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11d103466a0222c679a6be2408baa7298f57df0cc9f91fb0e92b85dd9364e0e1' 
  AND token = 'qBY16xhmkgs8TNJf+j30a4jobRWSXed71y619pykzRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}