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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ba51034baae76a6765b4bd9d1a27f2a881792c22226d3d6f588e3f30704259' 
  AND token = '6gUHJTSy2wT0gULW92oQqfAqeDxu7o8l3N42LOFQQVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}