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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f01a01eef040ba9b5d796f6135289d9eb551ed0c0015f3b9ad9895abfd94b1d6' 
  AND token = 'aVoSVZTcB3sacoi/dFNpRcKmGt0bRL3T21KrrpDYKHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}