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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83935db72c104437b2789529fb7af8d518af1c03aa2e9aae0be8be417812f3b2' 
  AND token = 'm8z+GPnOTS3HtCTcWQhDcHqOR2wovTnnuuIjHIkicVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}