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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c79bc7008a42afb74da910ded14c3e8b4b6161c1f2fa4d7300559ea0b1587ae0' 
  AND token = 'ZK3bb71zPpQVTtqq3N5+5b2a0iCRCq3p48UXMdKmgmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}