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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09143207684be6af33a36ed7011cc9e8fd0382a3ddc55731d8f2293b2e838340' 
  AND token = 'F2JEkM+mia/DQ5N3DcchWxEbjFWoQqs2Tmu7+jcMToQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}