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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b6249f134dfd81fa5d6e21d7ebdc637dc47ea2aadbca53f5e2a1f977466bb34' 
  AND token = 'z3SlAEKl+EentkYRFfbLsSgVhdDKOhGGruqb5268ttE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}