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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f891390fafeb9d820ede1cc1def659ae20a998561751078cad9c79bc814f95b3' 
  AND token = 'yI9fYv0709VuQdv++SXBrr0t8nuouKTY337pfuqJJes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}