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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd78626d5871d976a9264b93155630f4f49c3a5537269603c578643a17abda25' 
  AND token = 'ETNMpL5+swcbcJDGva+xQA0tA9+xnxc46qhheEBSpIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}