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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aa300e1e03f4695e0e4794443880dc30ae53309632d864557995fc5b5aa2ff2' 
  AND token = 'qz8R8+M1f0IT+9OWfL3Z8rxGO1h3Kc95azZFe3QT2bY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}