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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3653240d7dae1552fe1e2a6b25e9da3e61eda37d0b2550924acf6f3beeda4704' 
  AND token = '/HOGf4By+SaBdPPD7nUr/v8CTwRHcHm11KdREg0CADs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}