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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce84a0df346795f9a5ac14c7fb0995d26ec44d300cfd06b3f8fe774440fe038' 
  AND token = 'aTEDYDcIaP0GkYB6xImcVTSEMrRT//8gPCxoG2VWkdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}