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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de17c364c23c61af007d0f786b9c87d9b9cd9f2e54e7d3f5ebabf5fd7b9f152' 
  AND token = 'CAcpdikb66czOXuJ5j2aaI76DB0E5FKfSqFAlVnDdlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}