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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22bc43ff237cac8bf82d56125e0ce40d5d1becda1bd7af80126944c88e2eed12' 
  AND token = 'yA5ZF4TkmcwTHaMma8e9M97PsBVhA7i/kir9DOYZZDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}