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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0e8dc75495d7a650829e6becf91a01f9664460e31dc0b012221968df11b38e' 
  AND token = '8MPqsP1lDHgfcz++LY1zufQmT4VpGnnkSjXT/r6ujPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}