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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a53f054afdaf02715c2600491a67846a9de0879a3df0c9d1b746a68a7b0a00' 
  AND token = 'g8xiqL36DWKoQOs6bz/MOhuj6Z1b67d8UdEoGoC2C0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}