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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c71920b9d15c8c4e96dd45b8f06a16f21452dae522494578f9112b83158b619f' 
  AND token = 'IzfjHE9f2DEMpqZro6hKWmyL3BPs8UYA/1FoiWt7W2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}