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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff18897c3d2d1bd740f28c6e31fcd6ec51e9f7589de56b873be8523791ab2e22' 
  AND token = 'wjg8PmmRwnVck+Eycm7cvySlDftRDnygULBXkm+R2Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}