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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2103f77c644e3defb795eaed20b6b8e8771b2b136f85698882ca5b32b95d6593' 
  AND token = 'uhvuW4fGeb4bKad6flfi8beL4+i0hXTAUHSFgukQNfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}