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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a646ea7f3994ebcc29ea4ea501ef35d6fd6839dac9f17aa4f9291f132c3e36ad' 
  AND token = '/ObIpgE3/Ru2Uju4IvSbuRsiIe1laVNUi5B8uFvGjhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}