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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a693b741b21a4bdfa172b5f521ed4561a2056d081d519c885e0669e40d3931d' 
  AND token = 'vTheIVidbQd2lj2SAPbY1fykOvpNFGRJgVgrE1PqcqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}