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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0102b08f1ab732f39592adf10434bbc87aa89c1fc75a6e6f30a184d5499ecc7' 
  AND token = 'eWl8JM2fmO/3fP25qfGkYrDyLx+f1GgPd4aW+UHlKZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}