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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df87b6a52ffb75e1237411f85a2ab889b651dd590516f2a08f8ec85b24b7516e' 
  AND token = 'Vtl0BWxSlvcHpOn4A64atqizEruRpBS82St6DJj+V8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}