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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5981af29ad8c38739cc4fe7587d00fffd4e0413be327bf23201a5fdae1cd8cf' 
  AND token = 'e5ZV4mRBByPb5DB/74kgeeyQbl7gxsjrmtZ9mS2m+S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}