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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aad37124e33d35369c39a63e29b69735fd7aa04ec5903e857c09b5a0e12b607' 
  AND token = 'bvLO3qmAmV6cxKfDSyVCM1kHf/nNTx7SRLafnVZ9n5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}