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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf41d49bf160686e832deb9f0f893f1721ef17b4a1193ec10c360eafe3cef7bc' 
  AND token = 'I6YNVGcW/q7rJItpmcMmLe19rNMVFbBqqeOoe2jQyJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}