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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e56522825d04f96cae82aba2b670a870b7a07f409e9a7f4b40f51263518111c2' 
  AND token = 'H98eXnj6V8pQalj0LfoxKICCHFP2nwxsOd5ypv0Q3So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}