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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1bf0c24b6c4b9729fc4d158eb6aca06a02af42da0611dd5391da4c3946ff08' 
  AND token = 'RY8dXe+nRZZiYZVQG5qwUhtg8akCAp+r890FwhNCLh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}