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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cba1c101ccdea460a9faa78d870b74f320682067094c3bfefddfa04d6d63531' 
  AND token = 'IG/knujPBAmzDaitA3rugGSU3KBqobr0pwUZ/1Se7Dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}