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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a6b6b654d0609898f01c26e4c2314f72d6fe3b09f30150df34c371e2d31a788' 
  AND token = '8f0xa5KGvEH+5UJFrAmqsidLSZtHPXt6ZmSHPCQ141A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}