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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406547195daae16ddb2897ec51b02f81aa65294ca3f2bc796d2e149298920201' 
  AND token = 'M+9NwC5i3B/ZS6GMncwgKT6I/27wpiSfy26iAaeeXPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}