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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed745dd8a41b32a3508a7840a5ffbd8c23954f9cdffad0853a84e8737f0fce43' 
  AND token = 'Muw7cASVJMdnRF724F+EC8FmU8U8Y5W8p4mjGai5AIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}