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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d3405949d88168aa1209904e0d9033df5ad9aed2fb02350bcc7d9aa02941e01' 
  AND token = 'Mw2fztEJTYmTdbP9mI24qEF8VAViJ1N9YwJaetGv4gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}