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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75caea9989bbe10f13805a5ed255f036bdb62e9dca20390ff5e510e5baf2d075' 
  AND token = 'DGtcKUNDYxB496ZqCSc9K9r1QXUTL0qrv2333S/S6xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}