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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52aab3cce0cfeafe63e2f4f7bb1e0e19eddeb0b89ae78270bcd680b85bff4697' 
  AND token = '39+Gpcs5kam+nBRP+9fgMubA6+HRXvHTdK5mBKs0QpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}