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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae4e60fd88842955813f8080065519d9bb440faedd5cbff78fb099ed10c0a05' 
  AND token = 'xk8rAkaie/F3PyQrMO2gWlj+sf6aICCD4YhePrqN8VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00130

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}