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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f34586462af2b64dab4e163e80c8601b68dd2f342105f4267fad5f657cf3dd55' 
  AND token = '0TZcD1ESD0vwzIhvfiEDTO0uK7hUUSzPMMu97NOyE6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}