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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4af12f84ce42f56036a15ceb13278138d7072070a6032aab42973397076b84c' 
  AND token = 'JGslSyyZyHd7SpD2TWADTsqtkoIVqPvTk+tnSf/AHLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}