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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '948a00b20589830f66d53b798fc7674832e29fa31e1471ab52f9bc1b1f819be1' 
  AND token = 'Zp9Ly+JPl408XtxPFtY+84YUYMYP1DC1PG7RIO25kns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}