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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5805299f271de356031680c7749115b94fc64b1b26b5afc77f6929fb94fb977b' 
  AND token = 'Swiq7DdjqeOo0KIIN16UYiIXOkfxmVWVmUcZG3S5V4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}