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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd2f2bdbc70eabae5d6b84e717d0dcd290c356565c288c9b51bdf68c968cc232' 
  AND token = 'jyiKHPtOzXjuZ33dsL+qewXud31f47wVvXKph+ExuNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}