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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64327863d3a055781ed0d251652386395fea42bafcbd0a5803133977dccea373' 
  AND token = 'AnjU7uRv7sAZN7XQD7uzeAr+QcbgLdn9O4i4utHWTp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}