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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99b21973fb94d5bec0b26386e46ea2db0e51b30196fbc7b2533808c626ec7367' 
  AND token = 'P/1EIAuRr+DSRNKQPNaGbJyfV8DfC49mq2G88RRCIto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}